GENOTOUL: Key highlights
Discover the 2019 highlights of the constituent platforms of the Genotoul GIS in a dedicated booklet. TRI-Genotoul contributes by showcasing two advances: Imaging and cytometry at the heart of human adipose tissue Automatically analysing the mechanical properties of cell populations by Atomic Force Microscopy View the brochure
High-Throughput Imaging & Biocontrol
One of the current agronomic challenges relates to the identification of more environmentally friendly plant protection products. This research requires the screening of several thousand candidate molecules, notably by evaluating their effects on the development of plant-pathogenic microorganisms. To this end, thanks to funding from the Occitanie Region / ERDF funds […]
A new Zeiss Lattice SIM super-resolution microscope
The TRI-Genotoul platform, IPBS site, has just acquired the new Lattice Structured Illumination Microscopy (SR-SIM) technology, developed by Nobel Prize winner Eric Betzig. The IPBS platform is one of the first to receive this equipment in France. In particular, this device will help overcome technological barriers related to speed […]
A new tissue-sculpting force generation mechanism
Apoptosis, or programmed cell death, was long considered to be a simple mechanism for eliminating surplus cells. We now know that its role goes far beyond this, conditioning tissue patterning. Cells about to die thus transiently deform the tissue surrounding them and contribute to its final morphology. [...]
A hyperactive mutant of the RNA polymerase dedicated to ribosome synthesis
Ribosomes are the structures within cells responsible for protein production. They are composed of an assembly of molecules including RNA polymerase I, an enzyme specifically in charge of synthesising RNA components. Researchers have managed to isolate a mutant polymerase that is more active than the normal enzyme. The existence of this […]
3 & 4 Oct: Prototyping and Open Science Exchange Days 🗓 🗺
The “Prototypes and Device Control” group of RT-MFM (Multidimensional Fluorescence Microscopy - CNRS) and the Laboratory for Analysis and Architecture of Systems (LAAS-CNRS) are organising the second meeting on the prototyping of scientific instrumentation. This day, supported by GIS Genotoul, is an opportunity to discover, share and discuss innovative scientific instrumentation prototyping projects [...]
Hydathodes rescued from oblivion
Hydathodes are unique structures in more ways than one. Extensively described in the literature up until the 1970s, these organs subsequently fell into obscurity. With the assistance of the FRAIB imaging platform, L. Noël's team (LIPM) is bringing back to light the multiple roles played by these very particular structures, acting simultaneously as a safety valve [...]
high-pressure cryofixative
The METi platform has just acquired a new high-pressure cryofixation device for sample preparation in electron microscopy. Thanks to a pressure of 2300 bar and a cooling rate of approximately -15000°C/s, this equipment enables ultra-rapid freezing of samples of various sizes in order to immobilise them in a state as close as possible [...]
TRI, renewal of the NF X 50-900 standard
In January 2014, the Toulouse Cell Imaging Research Technological Platform, which has IBiSA labelling and is already ISO 9001 certified, was the first platform to be certified according to the new NFX 50-900 standard. Following this new audit, this certification has been successfully renewed. The NFX 50-900 standard was drawn up primarily […]
Fighting bacteria with Antabio
The company Antabio and the TRI-Genotoul imaging platform at the IPBS have just obtained ERDF funding to accelerate the development of therapeutic strategies against infections linked to the bacterium Pseudomonas aeruginosa, a common pathogen in chronic respiratory infections. Bacterial resistance to antibiotics is a major threat to human health. If this threat […]