Volume EM refers to a set of revolutionary methods enabling 3D imaging at very high resolution of the ultrastructure of large sample volumes using scanning electron microscopes coupled with various automated serial sectioning techniques. These methods make it possible to obtain, within a few hours or days, high-content results that would previously have required, at best, months or even years of work. Although still relatively underdeveloped in France, this type of approach is experiencing very rapid growth on an international scale, finding applications in numerous fields of research.
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