On this page you will find our main areas of expertise in the field of small animal imaging, an example of collaboration, and resources that are particularly dedicated to the study of this disciplinary field.
Our areas of expertise
Gene therapy
Observation of a ganglion by MacroFluo
Evaluation of vectors for gene transfer
- Monitoring of reporter gene expression over time
- Monitoring of the regulation of gene expression
Cancerology
Characterization of tumor models and study of biodistribution and pharmacokinetics in vivo
- Monitoring of tumor growth over time
- Kinetics and biodistribution of compounds of interest (new drugs, proteins, nanoparticles, etc.)
- Evaluation of the antitumor activity of drugs: longitudinal monitoring and comparison of tumor development of a treated group and an untreated control group
- Tests and development of labels (biodistribution)
Functional studies of microcirculation and the tumor microenvironment
- Analysis of blood and lymphatic circulation
- Monitoring of angiogenesis and blood vessel permeability
Functional and dynamic studies of immune cells
- Studies of the behavior of cells: Migration, recruitment (tumors, ganglia, skin, etc.)
- Use of fluorescent transgenic models, ex vivo and in vivo cell labeling
An example of collaboration: : Vectalys
The Vectalys company, which specializes in the development of viral vectors, was looking for resources to directly analyze the action of viruses within organisms..
After contacting the platforms of the TRI-Genotoul network, Vectalys engineers were steered to the specialized platform and its adapted resources, and subsequently trained to work independently (an essential condition for the preservation of an industrial confidentiality). This collaboration, which began in 2008, is still in action today.
Our specially dedicated resources for small animals
 MacroFluo (non-invasive) |
 Wide-field (intravital) |
 Confocal Multi-photon confocal (intravital) |
 Volatile anesthesia system |
 Ventilated closet |
